Thanks for the explanation, but I still don’t quite see how this is special, afaik LDF is analogous to van der Waals force? Is this basically the same as a “loose” active site? (Ie. Can bind a range of similar substrates) Is it because the LDF force acts on an allosteric site of the enzyme and thus changes the active site? I also don’t understand their use of the term “4D”. (Sorry for being difficult, just trying to understand the significance of the paper)
shreddy_scientist