I'm not sure what to offer because my disability has made it so that I have had to give up most games.
I have a few issues, but the main problem when it comes to gaming is dystonia. I get cramps in my hand, wrist, arm, and shoulder from repetitive or rapid mouse clicking or button pressing, from having to heavily use a thumb stick, and similar motions. It's made worst by the fact that controllers keep getting bigger while my hands stay tiny. This has made it so that I can only play a very limited selection of games. I haven't found any solutions.