When I was younger, I quit Bioshock when I ran into a Big Daddy that I just could not kill. The difficulty was on normal and I refused to change it to easy out of stubbornness. In retrospect, I think I missed a very cool gaming experience because of that.
I’m just now playing Prey (2017) on story mode, not respecting any of the enemies at all, and still having a really good time. On the flip side, if Elden Ring had the ability to adjust difficulty level, I think it would ruin the game.