I’ve used Windows for a bit more than a decade, and I only found out its VFS is case-insensitive (by default) after I fully ditched the OS, when a bunch of Electron applications created directories with different cases - nothing ever broke because of it, save for a single Godot game.
Personally, I think case-insensitivity seldom makes sense, though I’m also aware that not everyone [knows how / is able] to properly operate a keyboard.