Before Andy Sum made Crossy Roads he made a game called Game of the Year: 420 Blaze It VS. xxXilluminatiXxx (www.gameoftheyear420blazeit.com)
It was created around the peak of the MLG trend and is absolutely covered in memes. I just find it funny that came out around the same time as their other game Crossy Roads which would go on to be quite popular even appearing in numerous arcades.